Essential Developmental Biology, 2nd Edition
Essential Developmental Biology, 2nd Edition
Author: Jonathan M. W. Slack
ISBN: 9781405122160
Pages: 448
Format: 22 Χ 28
Binding: Paperback
Pub. Year: 2005
• Includes new chapters on Evolution & Development, Gut Development, & Growth and Aging.
• Contains expanded treatment of mammalian fertilization, the heart and stem cells.
• Now features a glossary, notated further reading, and key discovery boxes.
• Illustrated with over 250 detailed, full-color drawings.
• Accompanied by a dedicated website, featuring animated developmental processes, a photo gallery of selected model organisms, and all art in PowerPoint and jpeg formats.
Table of Contents
Preface.
Section 1: Groundwork.
1 The Excitement of Developmental Biology.
• Where the subject came from.
• Central position in biology.
• Impact on society.
• Future impact.
2 General Features of Development.
• Genomic equivalence, cloning of animals.
• Gametogenesis.
• Early development.
• Morphogenetic processes.
3 Developmental Genetics.
• Developmental mutants.
• Screening for mutants.
• Cloning of genes.
• Transgenesis.
• Limitations of developmental genetics.
4 Experimental Embryology.
• Normal development.
• Developmental commitment.
• Acquisition of commitment.
• Homeotic genes.
• Criteria for proof.
5 Techniques for the Study of Development.
• Microscopy.
• Study of gene expression by biochemical methods.
• Study of gene expression by in situ methods.
• Reporter genes.
• Microinjection.
• Cell-labelling methods.
• Cell sorting.
Section 2: Major model organisms.
6 Model Organisms.
• Availability and cost.
• Access and micromanipulation.
• Genetics and genome maps.
• Relevance.
7 Xenopus.
• Oogenesis, maturation, fertilization.
• Embryonic development.
• Experimental methods.
• Regional specification.
• Inductive interactions.
8 The Zebrafish.
• Normal development.
• Mutagenesis.
• Regional specification.
9 The Chick.
• Normal development.
• Regional specification of the early embryo.
• Description of organogenesis in the chick.
10 The Mouse.
• Mammalian fertilization.
• Normal development.
• Technology of mouse development.
• Regional specification in development.
• Other topics in mouse development.
11Drosophila.
• Insects.
• Normal development.
• Drosophila developmental genetics.
• Overview of the developmental program.
• The dorsoventral pattern.
• The anteroposterior system.
12 Caenorhabditis elegans.
• Normal development.
• Regional specification in the embryo.
• Analysis of postembryonic development.
• Programmed cell death.
Section 3: Organogenesis.
13 Tissues and stem cells.
• Types of tissue.
• Tissue renewal.
• Skin.
• Intestine.
• Haematopoietic system.
14 Development of the Nervous System.
• Overall structure and cell types.
• Anteroposterior patterning of the neural plate.
• Dorsoventral patterning of the neural tube.
• Neurogenesis and gliogenesis.
• The neural crest.
• Development of neuronal connectivity.
15 Development of Mesodermal Organs.
• Somitogenesis and myogenesis.
• The kidney.
• Germ cells and gonads.
• Limb development.
• Heart and blood vessels.
16 Development of Endodermal Organs.
• Normal development.
• Determination of the endoderm.
• The pancreas.
17 Drosophila Imaginal Discs.
• Metamorphosis.
• Genetic study of larval development.
• Mitotic recombination.
• Disc development.
• Regional patterning of the wing disc.
Section 4: Growth, regeneration and evolution.
18 Growth and ageing.
• Size and proportion.
• Growth in stature.
• Ageing.
• Postnatal disorders of growth and differentiation.
19 Regeneration of Missing Parts.
• Distribution of regenerative capacity.
• Planarian regeneration.
• Vertebrate limb regeneration.
20 Evolution and Development.
• Macroevolution.
• The primordial animal.
• What really happened in evolution?.
.
Appendix.
Key Molecular Components.
• Genes.
• Transcription factor families.
• Signalling systems.
• Cytoskeleton.
• Cell adhesion molecules.
• Extracellular matrix components.
.
Glossary.
Index
Site map