Parasitic Nematodes: Molecular Biology, Biochemistry and Immunology
Readership
Advanced students and researchers in human and veterinary parasitology, plant nematology and immunology
Key Features
• An up to date summary of this important and rapidly expanding area of research
• No other published titles focus specifically on these aspects
Main Description
Currently more than one third of the world's population are infected with parasitic nematodes, and infection of domestic animals and crop plants remains a substantial drain on human wellbeing and economies. An understanding of the structure and function of genes, membrane and antigens of parasitic nematodes will help develop strategies to eliminate them or reduce their impact.
Reviews
• "Anyone interested in parasitic diseases caused by nematodes, from both a research and teaching perspective, should purchase this book.Importantly, the presentation is excellent and continues the high standards of CABI Publishing.This book represents a timely and informative contribution to any parasitological library, and as stated earlier, is a most useful resource for researchers and teachers in the field."
Australian Veterinary Journal, Vol 80, Nov 2002
Main Contents
Part I: Genetics and phylogeny
• Molecular analysis of nematode evolution, M L Blaxter
• The Wolbachia endosymbionts of filarial nematodes, C Bandi, C Genchi, T J C Anderson and M L Blaxter
• Forward genetic analysis of plant-parasitic nematode-host interactions, Opperman
• Identification of parasitic nematodes and study of genetic variability using PCR approaches, R Gasser
• Diversity in populations of parasitic nematodes and its significance, M Viney
Part II: Host modulation and manipulation - making themselves at home
• New insights into the intestional niche of Trichinella spiralis, J A Appleton
• Genetic reprogramming of mammalian skeletal muscle cells by Trichinella spiralis, D P Jasmer
• Plant parasitic nematodes, A F Bird and D McK Bird
Part III: Specialist products and activities
• The nematode cuticle: synthesis, modification and mutants, A Page
• Chitinases of filarial nematodes, R Adam, B Drabner and R Lucius
• Acetylcholinesterase secretion by nematodes, M E Selkirk, S M Henson, A S Hussein and W S Russell
• The surface and secreted antigens of Toxocara canis: genes, protein structure and function, R M Maizels and AC Loukas
• Nematode gut peptidases, proteins and vaccination, D P Knox, P J Skuce, G F Newlands and D L Redmond
• Metabolic transitions and the role of the pyruvate dehydrogenase complex during development of Ascaris suum, P R Komuniecki and R Komuniecki
• Novel carbohydrate structures, A Dell, S M Haslam and H R Morris
• Structurally novel lipid binding proteins, M W Kennedy
Part IV: Immunology and immunomodulation
• T helper cell cytokine reponses during intestinal nematode infection: Induction, regulation, and effector function, D Artis and R K Grencis
• Gut immunopathology in helminth infections - paradigm lost? C Lawrence, M W Kennedy and P Garside
• Immunomodulatory properties of a phosphorylcholine-containing filarial nematode secreted glycoprotein, W Harnett and M M Harnett
Part V: Neurobiology
• Nematode neuropeptides, A Maule, N Marks and D W Halton
• Neurobiology of nematode muscle: ligand-gated ion channels and anti-parasitic drugs, R J Martin, A P Robertson, M A Valkanov, J Purcell and S Lowden
